Article
Common Genetic Variants Modulate the Electrocardiographic Tpeak-to-Tend Interval.
American journal of human genetics - 4 Jun 2020
Ramírez Julia, van Duijvenboden Stefan, Young William J, Orini Michele, Lambiase Pier D, Munroe Patricia B, Tinker Andrew
Abstract excerpt
Sudden cardiac death is responsible for half of all deaths from cardiovascular disease. The analysis of the electrophysiological substrate for arrhythmias is crucial for optimal risk stratification. A prolonged T-peak-to-Tend (Tpe) interval on the electrocardiogram is an independent predictor of increased arrhythmic risk, and Tpe changes with heart rate are even stronger predictors. However, our understanding of...
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