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Article

Genetics of Human Longevity From Incomplete Data: New Findings From the Long Life Family Study.

The journals of gerontology. Series A, Biological sciences and medical sciences - 8 Oct 2018

Yashin Anatoliy I, Arbeev Konstantin G, Wu Deqing, Arbeeva Liubov S, Bagley Olivia, Stallard Eric, Kulminski Alexander M, Akushevich Igor, Fang Fang, Wojczynski Mary K, Christensen Kaare, Newman Anne B, Boudreau Robert M, Province Michael A, Thielke Stephen, Perls Thomas T, An Ping, Elo Irma, Ukraintseva Svetlana V

Abstract excerpt

The special design of the Long Life Family Study provides a unique opportunity to investigate the genetics of human longevity by analyzing data on exceptional lifespans in families. In this article, we performed two series of genome wide association studies of human longevity which differed with respect to whether missing lifespan data were predicted or not predicted. We showed that the use of predicted lifespan...

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PMID: 30299504
DOI: 10.1093/gerona/gly057
PMCID: PMC6175028

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