Article
T-T cyclobutane dimers are misinstructive, rather than non-instructive, mutagenic lesions.
Molecular & general genetics : MGG - 1 Jun 1990
Lawrence C W, Banerjee S K, Borden A, LeClerc J E
Abstract excerpt
The lesions produced by SOS-dependent mutagens in Escherichia coli are commonly referred to as nonpairing or non-instructive. Although these terms are likely to be appropriate for some lesions, particularly the abasic site, for others, such as the cyclobutane dimer, their suitability is open to question. To address this question, we have compared the error frequencies and spectra that result when a uniquely...
Topics
- Base Sequence
- Cyclobutanes
- Escherichia coli
- Molecular Sequence Data
- Mutation
- Pyrimidine Dimers