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Article

Dysregulation of innate immunity in hepatitis C virus genotype 1 IL28B-unfavorable genotype patients: impaired viral kinetics and therapeutic response.

Hepatology (Baltimore, Md.) - 1 Aug 2012

Naggie Susanna, Osinusi Anu, Katsounas Antonios, Lempicki Richard, Herrmann Eva, Thompson Alexander J, Clark Paul J, Patel Keyur, Muir Andrew J, McHutchison John G, Schlaak Joerg F, Trippler Martin, Shivakumar Bhavana, Masur Henry, Polis Michael A, Kottilil Shyam

Abstract excerpt

UNLABELLED: Recent studies have shown that a single-nucleotide polymorphism upstream of the interleukin-28B (IL28B) gene plays a major role in predicting therapeutic response in hepatitis C virus (HCV)-infected patients treated with pegylated interferon (PEG-IFN)/ribavirin. We sought to investiga...

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Identifiers

PMID: 22331604
DOI: 10.1002/hep.25647
PMCID: PMC3361636

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22331604-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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