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Human Immunodeficiency Virus, Restriction Factors, and Interferon

20 Aug 2009

Abstract excerpt

Recent discoveries have revealed previously unappreciated complexity with which retroviruses interact with their hosts. In particular, we have become aware that many mammals, including humans, are equipped with genes encoding so-called "restriction factors," that provide considerable resistance to retroviral infection. Such antiretroviral genes are sometimes constitutively expressed, and sometimes...

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PMID: 19694548
DOI: 10.1089/jir.2009.0077

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