Developmental analysis of the external granular layer in the <i>Meander tail</i> mutant mouse: Do cerebellar microneurons have independent progenitors?

Abstract excerpt

The cerebellum of the meander tail mutant mouse (mea/mea) is characterized by an apparently normal cytoarchitecture posteriorly with an abrupt transition to an abnormal anterior region. Anteriorly, there is abnormal foliation, a drastic reduction in the granule cells (GC) population, disorganization of the Purkinje cells (PC), and a virtual absence of Bergmann glial processes. In this paper we analyze the...

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