Article
The activities of two Ets-related transcription factors required for Drosophila eye development are modulated by the Ras/MAPK pathway.
Cell - 15 Jul 1994
O'Neill E M, Rebay I, Tjian R, Rubin G M
Abstract excerpt
We show that the activities of two Ets-related transcription factors required for normal eye development in Drosophila, pointed and yan, are regulated by the Ras1/MAPK pathway. The pointed gene codes for two related proteins, and we show that one form is a constitutive activator of transcription,...
Topics
- Animals
- Calcium-Calmodulin-Dependent Protein Kinases
- DNA-Binding Proteins
- Drosophila
- Drosophila Proteins
- Extracellular Signal-Regulated MAP Kinases
- Eye
- Eye Proteins
- Gene Expression Regulation
- Genes, Insect
- Genes, ras
- Models, Biological
- Morphogenesis
- Nerve Tissue Proteins
- Phenotype
- Photoreceptor Cells, Invertebrate
- Proto-Oncogene Proteins
- Proto-Oncogene Proteins p21(ras)