Article
Regulation of JNK by Src during Drosophila development.
Science (New York, N.Y.) - 14 Jan 2000
Tateno M, Nishida Y, Adachi-Yamada T
Abstract excerpt
In Drosophila, the Jun amino-terminal kinase (JNK) homolog Basket (Bsk) is required for epidermal closure. Mutants for Src42A, a Drosophila c-src protooncogene homolog, are described. Src42A functions in epidermal closure during both embryogenesis and metamorphosis. The severity of the epidermal closure defect in the Src42A mutant depended on the amount of Bsk activity, and the amount of Bsk activity depended on...
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