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Identification of TBX15 as an adipose master trans regulator of abdominal obesity genes

2 Aug 2021

Abstract excerpt

BACKGROUND: Obesity predisposes individuals to multiple cardiometabolic disorders, including type 2 diabetes (T2D). As body mass index (BMI) cannot reliably differentiate fat from lean mass, the metabolically detrimental abdominal obesity has been estimated using waist-hip ratio (WHR). Waist-hip ratio adjusted for body mass index (WHRadjBMI) in turn is a well-established sex-specific marker for abdominal fat and...

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PMID: 34340684
DOI: 10.1186/s13073-021-00939-2

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