Article
Genetic variations in the CYP17A1 and NT5C2 genes are associated with a reduction in visceral and subcutaneous fat areas in Japanese women.
Journal of human genetics - 1 Jan 2012
Hotta Kikuko, Kitamoto Aya, Kitamoto Takuya, Mizusawa Seiho, Teranishi Hajime, Matsuo Tomoaki, Nakata Yoshio, Hyogo Hideyuki, Ochi Hidenori, Nakamura Takahiro, Kamohara Seika, Miyatake Nobuyuki, Kotani Kazuaki, Komatsu Ryoya, Itoh Naoto, Mineo Ikuo, Wada Jun, Yoneda Masato, Nakajima Atsushi, Funahashi Tohru, Miyazaki Shigeru, Tokunaga Katsuto, Masuzaki Hiroaki, Ueno Takato, Chayama Kazuaki, Hamaguchi Kazuyuki, Yamada Kentaro, Hanafusa Toshiaki, Oikawa Shinichi, Yoshimatsu Hironobu, Sakata Toshiie, Tanaka Kiyoji, Matsuzawa Yuji, Nakao Kazuwa, Sekine Akihiro
Abstract excerpt
Visceral fat accumulation has an important role in increasing the morbidity and mortality rates, by increasing the risk of developing several metabolic disorders, such as type 2 diabetes, dyslipidemia and hypertension. New genetic loci that are associated with increased systolic and diastolic blood pressures have been identified by genome-wide association studies in Caucasian populations. This study investigates...
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