Article
Association of single nucleotide polymorphism Rs2236518 in PRDM16 gene with BMI in Chinese males.
Acta pharmacologica Sinica - 1 May 2013
Yue Hua, He Jin-wei, Ke Yao-hua, Zhang Hao, Wang Chun, Hu Wei-wei, Gu Jie-mei, Fu Wen-zhen, Hu Yun-qiu, Li Miao, Liu Yu-juan, Zhang Zhen-lin
Abstract excerpt
AIM: PRD1-BF-1-RIZ1 homologous domain containing protein-16 (PRDM16) is a cell-autonomous transcriptional component that stimulates the development of brown fat cells. The aim of this study was to investigate the contribution of genetic variants of PRDM16 to obesity-related phenotype variations in Chinese. METHODS: A total of 3204 subjects (consisting of 400 male-offspring nuclear families, 401 female-offspring...
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