Article
Association between nerve growth factor gene polymorphism and executive dysfunction in Japanese patients with early-stage Alzheimer's disease and amnestic mild cognitive impairment.
Dementia and geriatric cognitive disorders - 1 Jan 2011
Nagata Tomoyuki, Shinagawa Shunichiro, Nukariya Kazutaka, Nakayama Ritsuko, Nakayama Kazuhiko, Yamada Hisashi
Abstract excerpt
BACKGROUND/AIMS: To address the clinical neurocognitive roles of nerve growth factor (NGF) genetic polymorphism in early-stage Alzheimer's disease (AD) and amnestic mild cognitive impairment (A-MCI), we investigated the association between this single-nucleotide polymorphism (SNP) and executive dysfunction as a nonmemory cognitive impairment. METHODS: Among 200 outpatients with dementia and MCI whose NGF SNP...
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