Article
Polymorphisms of the neurotrophic factor-3 (NTF-3) in Alzheimer's disease: rs6332 associated with onset time and rs6489630 T allele exhibited a protective role.
Journal of neurogenetics - 1 Jan 2015
Liu Mengyuan, Huo Ya Ruth, Wang Junwei, Liu Shuling, Liu Shuai, Wang Change, Wang Jinhuan, Ji Yong
Abstract excerpt
Because of its implications in neuroprotection, formation of long lasting memories and a disturbed function in Alzheimer's disease (AD), neurotrophin-3 (NTF-3) may represent an appropriate candidate gene conferring risk to AD. Recently, two single nucleotide polymorphisms (SNPs) (rs6489630 and rs6332) within the NTF-3 gene have been associated with AD in a Japanese population. Because of the importance of this...
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