Article
Plasma BDNF levels are correlated with aggressiveness in patients with amnestic mild cognitive impairment or Alzheimer disease.
Journal of neural transmission (Vienna, Austria : 1996) - 1 Apr 2014
Nagata Tomoyuki, Kobayashi Nobuyuki, Shinagawa Shunichiro, Yamada Hisashi, Kondo Kazuhiro, Nakayama Kazuhiko
Abstract excerpt
In the present study, we examined whether neuropsychiatric symptoms were correlated with plasma brain-derived neurotrophic factor (BDNF) levels as a state marker or were associated with the BDNF polymorphism Val66Met in patients with amnestic mild cognitive impairment (A-MCI) or Alzheimer disease (AD). One hundred and seventy-six outpatients with AD (n = 129) or A-MCI (n = 47) were selected and their plasma BDNF...
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