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Article

Association between brain-derived neurotrophic factor (BDNF) gene polymorphisms and executive function in Japanese patients with Alzheimer's disease.

Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society - 1 Sept 2011

Nagata Tomoyuki, Shinagawa Shunichiro, Nukariya Kazutaka, Ochiai Yusuke, Kawamura Satoshi, Agawa-Ohta Miyuki, Kasahara Hiroo, Nakayama Kazuhiko, Yamada Hisashi

Abstract excerpt

BACKGROUND: To address the functional roles of genetic polymorphisms of brain-derived neurotrophic factor (BDNF) in Alzheimer's disease (AD) from a neuropsychological aspect, we used a cross-sectional study design to investigate the association between novel single nucleotide polymorphisms (SNPs) of the BDNF gene (Val66Met (G196A) and C270T) and the Frontal Assessment Battery (FAB) score, which reflects executive...

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Identifiers

PMID: 21951954
DOI: 10.1111/j.1479-8301.2011.00364.x

Genes

BDNF

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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