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Article

Activation of β-catenin signaling in androgen receptor-negative prostate cancer cells.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Feb 2012

Wan Xinhai, Liu Jie, Lu Jing-Fang, Tzelepi Vassiliki, Yang Jun, Starbuck Michael W, Diao Lixia, Wang Jing, Efstathiou Eleni, Vazquez Elba S, Troncoso Patricia, Maity Sankar N, Navone Nora M

Abstract excerpt

PURPOSE: To study Wnt/β-catenin in castrate-resistant prostate cancer (CRPC) and understand its function independently of the β-catenin-androgen receptor (AR) interaction. EXPERIMENTAL DESIGN: We carried out β-catenin immunocytochemical analysis, evaluated TOP-flash reporter activity (a reporter of β-catenin-mediated transcription), and sequenced the β-catenin gene in MDA prostate cancer 118a, MDA prostate cancer...

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Share to beta Catenin
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22298898
DOI: 10.1158/1078-0432.CCR-11-2521
PMCID: PMC3271798

Genes

HAS2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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