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Article

δ-Catenin promotes prostate cancer cell growth and progression by altering cell cycle and survival gene profiles

10 Mar 2009

Abstract excerpt

BACKGROUND: delta-Catenin is a unique member of beta-catenin/armadillo domain superfamily proteins and its primary expression is restricted to the brain. However, delta-catenin is upregulated in human prostatic adenocarcinomas, although the effects of delta-catenin overexpression in prostate cancer are unclear. We hypothesized that delta-catenin plays a direct role in prostate cancer progression by altering gene...

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PMID: 19284555
DOI: 10.1186/1476-4598-8-19

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