Article
δ-Catenin, a Wnt/β-catenin modulator, reveals inducible mutagenesis promoting cancer cell survival adaptation and metabolic reprogramming.
Oncogene - 19 Mar 2015
Nopparat J, Zhang J, Lu J-P, Chen Y-H, Zheng D, Neufer P D, Fan J M, Hong H, Boykin C, Lu Q
Abstract excerpt
Mutations of Wnt/β-catenin signaling pathway has essential roles in development and cancer. Although β-catenin and adenomatous polyposis coli (APC) gene mutations are well established and are known to drive tumorigenesis, discoveries of mutations in other components of the pathway lagged, which h...
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