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Article

The C134W (402 C>G) FOXL2 mutation is absent in ovarian gynandroblastoma: insights into the genesis of an unusual tumour.

Histopathology - 1 Apr 2012

Oparka Richard, Cassidy Andrew, Reilly Stephanie, Stenhouse Alasdair, McCluggage W Glenn, Herrington C Simon

Abstract excerpt

AIMS: Ovarian gynandroblastomas are rare tumours that, by definition, comprise a combination of components resembling both female, typically granulosa cell tumour (GCT), and male, typically Sertoli or Sertoli/Leydig cell tumour (ST/SLT), sex cord/stromal differentiation. The histogenesis of these tumours is unknown and, in view of the very strong association between the C134W (402 C>G) FOXL2 mutation and...

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Source

Identifiers

PMID: 22296244
DOI: 10.1111/j.1365-2559.2011.04148.x

Genes

FOXL2

Provenance

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Related research

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The C134W (402 C>G) FOXL2 mutation is absent in ovarian gynandroblastoma: insights into the genesis of an unusual tumour.PMID 22296244Read ↗

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Ovarian Gynandroblastoma: A Rare Sex Cord-Stromal Tumor with Unique Morphological, Genetic, and Clinical Features-A Series of Two Patients with Clinicopathological and Molecular Analysis, and a Review of the Literature.Semantic proximity Read ↗

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FOXL2 Mutation Status in Sex Cord-stromal Tumors Cannot be Predicted by Morphology.Semantic proximity Read ↗

Novel FOXL2 Mutation in an Ovarian Adult Granulosa Cell Tumor: Report of a Case With Diagnostic and Clinicopathologic Implications.Semantic proximity Read ↗

The specificity of the FOXL2 c.402C>G somatic mutation: a survey of solid tumors.Semantic proximity Read ↗

Ovarian Sex Cord-Stromal Neoplasms: An Overview of Molecular Events and How to Correlate Morphology With Molecular FindingsSemantic proximity Read ↗

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A current perspective on the pathological assessment of <i><scp>FOXL</scp>2</i> in adult‐type granulosa cell tumours of the ovarySemantic proximity Read ↗

Adult-Type Granulosa Cell Tumors and FOXL2 MutationSemantic proximity Read ↗

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