Article
FOXL2 mutations in granulosa cell tumors occurring in males.
Archives of pathology & laboratory medicine - 1 Jul 2012
Lima Joema F, Jin Long, de Araujo Ana Rose C, Erikson-Johnson Michele R, Oliveira Andre M, Sebo Thomas J, Keeney Gary L, Medeiros Fabiola
Abstract excerpt
CONTEXT: Granulosa cell tumors comprise less than 5% of ovarian tumors in women and are much rarer in men, with only about 20 cases reported, to our knowledge. Recently, a somatic mutation of FOXL2 was reported in virtually all adult-type granulosa cell tumors in women. OBJECTIVE: To investigate FOXL2 mutations in granulosa cell tumors occurring in males. DESIGN: Five cases of an adult-type granulosa cell tumor...
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