Article
Adult granulosa cell tumours of the testis analogous to ovarian counterparts are exceptionally rare: analysis of a multicentric series and review of the literature.
Histopathology - 1 Mar 2026
Ricci Costantino, de Biase Dario, Maloberti Thais, Orsatti Agnese, Ulbright Thomas M, Idrees Muhammad T, Oliva Esther, Cornejo Kristine, Lobo João, Michalova Kvetoslava, Raspollini Maria Rosaria, Williamson Sean R, van Leenders Geert Jlh, Kao Chia-Sui, Maclean Fiona, Sangoi Ankur R, Osunkoya Adeboye O, Fiorentino Michelangelo, De Leo Antonio, Tallini Giovanni, Acosta Andres Martin
Abstract excerpt
AIMS: Testicular adult granulosa cell tumours (AGCTs) are rare and show several clinical-pathological differences with their ovarian counterparts. In a limited number of prior studies, FOXL2 p.Cys134Trp, the hallmark molecular alteration of ovarian AGCT, appeared to be infrequent in testicular AGCTs. However, the number of cases analysed to date is relatively small. METHODS AND RESULTS: Twenty testicular AGCTs...
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