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Article

The formation and stability of DC-SIGN microdomains require its extracellular moiety.

Traffic (Copenhagen, Denmark) - 1 May 2012

Liu Ping, Wang Xiang, Itano Michelle S, Neumann Aaron K, Jacobson Ken, Thompson Nancy L

Abstract excerpt

Dendritic cell-specific intercellular adhesion molecule (ICAM)-3-grabbing non-integrin (DC-SIGN) is a Ca(2+) -dependent transmembrane lectin that binds a large variety of pathogens and facilitates their uptake for subsequent antigen presentation. This receptor is present in cell surface microdomains, but factors involved in microdomain formation and their exceptional stability are not clear. To determine which...

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Identifiers

PMID: 22292921
DOI: 10.1111/j.1600-0854.2012.01337.x
PMCID: PMC3365552

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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