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Article

Signal sequence within Fc gamma RIIA controls calcium wave propagation patterns: apparent role in phagolysosome fusion.

Proceedings of the National Academy of Sciences of the United States of America - 15 Apr 2003

Worth Randall G, Kim Moo-Kyung, Kindzelskii Andrei L, Petty Howard R, Schreiber Alan D

Abstract excerpt

Calcium oscillations and traveling calcium waves have been observed in living cells, although amino acid sequences regulating wave directionality and downstream cell functions have not been reported. In this study we identify an amino acid sequence within the cytoplasmic domain of the leukocyte IgG receptor Fc gamma RIIA that affects the amplitude of calcium spikes and the spatiotemporal dynamics of calcium waves...

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Identifiers

PMID: 12676989
DOI: 10.1073/pnas.0836650100
PMCID: PMC153590

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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