Article
Transport of the IgE receptor alpha-chain is controlled by a multicomponent intracellular retention signal.
The Journal of biological chemistry - 14 Apr 2006
Cauvi David M, Tian Xufang, von Loehneysen Katharina, Robertson Michael W
Abstract excerpt
The human high affinity IgE receptor (FcepsilonRI) is a central component of the allergic response and is expressed as either a trimeric alphagamma2 or tetrameric alphabetagamma2 complex. It has been previously described that the cytoplasmic domain (CD) of the alpha-chain carries a dilysine motif...
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