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Article

A recurrent D-strand association interface is observed in β-2 microglobulin oligomers.

The FEBS journal - 1 Mar 2012

Colombo Matteo, de Rosa Matteo, Bellotti Vittorio, Ricagno Stefano, Bolognesi Martino

Abstract excerpt

β-2 microglobulin (β2m) is an amyloidogenic protein responsible for dialysis-related amyloidosis in man. In the early stages of amyloid fibril formation, β2m associates into dimers and higher oligomers, although the structural details of such aggregates are poorly understood. To characterize the protein-protein interactions supporting the formation of oligomers, three individual β2m cysteine mutants and their...

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Identifiers

PMID: 22289140
DOI: 10.1111/j.1742-4658.2012.08510.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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