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Article

A covalent homodimer probing early oligomers along amyloid aggregation.

Scientific reports - 30 Sept 2015

Halabelian Levon, Relini Annalisa, Barbiroli Alberto, Penco Amanda, Bolognesi Martino, Ricagno Stefano

Abstract excerpt

Early oligomers are crucial in amyloid aggregation; however, due to their transient nature they are among the least structurally characterized species. We focused on the amyloidogenic protein beta2-microglobulin (β2m) whose early oligomers are still a matter of debate. An intermolecular interaction between D strands of facing β2m molecules was repeatedly observed, suggesting that such interface may be relevant...

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Identifiers

PMID: 26420657
DOI: 10.1038/srep14651
PMCID: PMC4588566

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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