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Article

Analysis of p16(CDKN2A) methylation and HPV-16 infection in oral mucosal dysplasia.

Pathobiology : journal of immunopathology, molecular and cellular biology - 1 Jan 2012

Fonseca-Silva Thiago, Farias Lucyana Conceição, Cardoso Claudio Marcelo, Souza Ludmilla Regina de, Carvalho Fraga Carlos Alberto de, Oliveira Marcos Vinícius Macedo de, Barros Lucas Oliveira, Alves Lucas Rodrigues, De-Paula Alfredo Maurício Batista, Marques-Silva Luciano, Gomez Ricardo Santiago, Guimarães André Luiz Sena

Abstract excerpt

OBJECTIVE: The purpose of this study was to investigate the relationship between p16(CDKN2A) methylation and epithelial dysplasia (ED). We also evaluated the expressions of proteins related to methylation (DNMT3B and DNMT1). Finally, we tested whether HPV-16/18 or the dmt3b (C46359T) polymorphism...

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Source

Identifiers

PMID: 22285991
DOI: 10.1159/000334926

Genes

DNMT1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22285991-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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