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Article

Promoter methylation of cyclin A1 is associated with human papillomavirus 16 induced head and neck squamous cell carcinoma independently of p53 mutation.

Molecular carcinogenesis - 1 Sept 2011

Weiss Daniel, Basel Tuerker, Sachse Florian, Braeuninger Andreas, Rudack Claudia

Abstract excerpt

Aberrant promoter methylation of specific genes and infection with human papillomavirus 16 (HPV16) are known risk factors for the development of Head and Neck Squamous Cell Carcinoma (HNSCC). Little knowledge exists on the interaction of HPV16 infection and promoter methylation in HNSCC. The promoter methylation status of 12 genes (TIMP3, CDH1, CDKN2A, DAPK1, transcription factor 21 (TCF21), CD44, MLH1, MGMT,...

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Topics

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Share to Carcinoma, Squamous Cell
Share to DNA Methylation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Genes, p53

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Share to Human papillomavirus 16

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Source

Identifiers

PMID: 21563216
DOI: 10.1002/mc.20798

Genes

CCNA1
TCF21
DAPK1
TIMP3
CDH1
LARS2
MGMT
MLH1
RASSF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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