Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

P16 Methylation as an Early Predictor for Cancer Development From Oral Epithelial Dysplasia: A Double-blind Multicentre Prospective Study

6 Apr 2015

Abstract excerpt

BACKGROUND: Silencing of P16 through methylation and locus deletion is the most frequent early events in carcinogenesis. The aim of this study is to prospectively determine if early P16 methylation is a predictor for oral cancer development. METHODS: Patients (n = 181) with mild or moderate oral epithelial dysplasia (OED) were recruited into the double blind multicentre cohort. P16 methylation was analyzed using...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Epigenetics and DNA Methylation
Share to Head and Neck Cancer Studies
Share to Oral Health Pathology and Treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 26137587
DOI: 10.1016/j.ebiom.2015.03.015

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

P16 Methylation as an Early Predictor for Cancer Development From Oral Epithelial Dysplasia: A Double-blind Multicentre Prospective StudyPMID 26137587Read ↗

DNA methylation markers for oral pre-cancer progression: A critical reviewSemantic proximity Read ↗

A 115-bp MethyLight assay for detection of p16 (CDKN2A) methylation as a diagnostic biomarker in human tissuesSemantic proximity Read ↗

Inactivation of p16, RUNX3, and HPP1 occurs early in Barrett's-associated neoplastic progression and predicts progression riskSemantic proximity Read ↗

Whole-genome bisulfite sequencing reveals the alteration of DNA methylation during malignant transformation of oral mucosal cellsSemantic proximity Read ↗

Identification of Stage-Specific microRNAs That Govern the Early Stages of Sequential Oral Oncogenesis by Strategically Bridging Genetics and EpigeneticsSemantic proximity Read ↗

The Role of Methylation as an Epigenetic Marker in HPV‐Related Oral LesionsSemantic proximity Read ↗

DNA methylation analysis with nasal brushing for early diagnosis of sino-nasal malignant tumoursSemantic proximity Read ↗

Hypermethylation of the p16 gene in normal oral mucosa of smokersSemantic proximity Read ↗

Analysis of p16(CDKN2A) methylation and HPV-16 infection in oral mucosal dysplasia.Semantic proximity Read ↗

Expression of Minichromosome Maintenance 2 (MCM2), Ki-67, and Cell-Cycle-Related Molecules, and Apoptosis in the Normal-Dysplasia-Carcinoma Sequence of the Oral MucosaSemantic proximity Read ↗

p16 hypermethylation: a biomarker for increased esophageal cancer susceptibility in high incidence region of North East India.Semantic proximity Read ↗

Aberrant p16 methylation, a possible epigenetic risk factor in familial esophageal squamous cell carcinoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.