The Role of Methylation as an Epigenetic Marker in HPV‐Related Oral Lesions

Abstract excerpt

Oral and oropharyngeal cancers, caused by persistent human papillomavirus (HPV), have recently increased. Diagnostic methods often fail to assess precancerous lesion risk, delaying oral cancer diagnosis. New molecular biomarkers, particularly DNA methylation, are sought to better stratify patients' risk. The PreCursor-M+ (Fujirebio, Tokyo, Japan), which analyze hypermethylation of the two onco-suppressor FAM19A4...

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