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Article

Oral HPV16 Prevalence in Oral Potentially Malignant Disorders and Oral Cavity Cancers.

Biomolecules - 3 Feb 2020

Tang Kai Dun, Menezes Lilian, Baeten Kurt, Walsh Laurence J, Whitfield Bernard C S, Batstone Martin D, Kenny Liz, Frazer Ian H, Scheper Gert C, Punyadeera Chamindie

Abstract excerpt

The role of human papillomavirus type 16 (HPV16) in oral potentially malignant disorders (OPMD) and oral cavity carcinoma (OC) is still under debate. We investigated HPV16 prevalence in unstimulated saliva, oral rinse samples, oral swabs and tumour biopsies collected from OPMD (n = 83) and OC (n = 106) patients. HPV16 genotype, viral load, physical status (episomal vs. integrated) and tumour p16INK4a expression...

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Identifiers

PMID: 32028653
DOI: 10.3390/biom10020223
PMCID: PMC7072384

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