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Article

Epigenetic pathogenesis of human papillomavirus in upper aerodigestive tract cancers.

Molecular carcinogenesis - 1 Nov 2015

Talukdar Fazlur Rahman, Ghosh Sankar Kumar, Laskar Ruhina Shirin, Kannan Ravi, Choudhury Biswadeep, Bhowmik Arup

Abstract excerpt

Human papillomavirus (HPV) has been recently associated with squamous cell carcinoma of upper aerodigestive tract (SCC of UADT), but its possible role in promoting aberrant methylation in these tumors has largely remained unexplored. Herein, we investigated the association of HPV with aberrant methylation in tumor-related genes/loci consisting of the classical CpG Island Methylator Phenotype (CIMP) panel markers...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25213493
DOI: 10.1002/mc.22214

Genes

BRCA1
DAPK1
GSTP1
MLH1
RASSF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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