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Article

Evaluation of published single nucleotide polymorphisms associated with acute GVHD.

Blood - 31 May 2012

Chien Jason W, Zhang Xinyi Cindy, Fan Wenhong, Wang Hongwei, Zhao Lue Ping, Martin Paul J, Storer Barry E, Boeckh Michael, Warren Edus H, Hansen John A

Abstract excerpt

Candidate genetic associations with acute GVHD (aGVHD) were evaluated with the use of genotyped and imputed single-nucleotide polymorphism data from genome-wide scans of 1298 allogeneic hematopoietic cell transplantation (HCT) donors and recipients. Of 40 previously reported candidate SNPs, 6 were successfully genotyped, and 10 were imputed and passed criteria for analysis. Patient and donor genotypes were...

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Identifiers

PMID: 22282500
DOI: 10.1182/blood-2011-09-371153
PMCID: PMC3369619

Genes

CTLA4
HPSE
MTHFR

Provenance

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