Article
Microsatellite scanning of the immunogenome associates MAPK14 and ELTD1 with graft-versus-host disease in hematopoietic stem cell transplantation.
Immunogenetics - 1 Jun 2013
Harkensee Christian, Oka Akira, Onizuka Makoto, Middleton Peter G, Inoko Hidetoshi, Nakaoka Hirofumi, Gennery Andrew R, Ando Kiyoshi, Morishima Yasuo
Abstract excerpt
Graft-versus-host disease (GVHD) is the main complication after hematopoietic stem cell transplantation (HSCT). Evidence for non-HLA gene polymorphisms as a cause of GVHD lacks consistency, which is, in part, due to methodological issues of previous candidate gene association studies and small effect size of their results, demanding for larger scale and more robust approaches. Here, non-HLA gene polymorphisms...
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