Article
Confirmation of novel type 1 diabetes risk loci in families.
Diabetologia - 1 Apr 2012
Cooper J D, Howson J M M, Smyth D, Walker N M, Stevens H, Yang J H M, She J-X, Eisenbarth G S, Rewers M, Todd J A, Akolkar B, Concannon P, Erlich H A, Julier C, Morahan G, Nerup J, Nierras C, Pociot F, Rich S S
Abstract excerpt
AIMS/HYPOTHESIS: Over 50 regions of the genome have been associated with type 1 diabetes risk, mainly using large case/control collections. In a recent genome-wide association (GWA) study, 18 novel susceptibility loci were identified and replicated, including replication evidence from 2,319 families. Here, we, the Type 1 Diabetes Genetics Consortium (T1DGC), aimed to exclude the possibility that any of the 18...
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