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Article

Type 1 diabetes: evidence for susceptibility loci from four genome-wide linkage scans in 1,435 multiplex families.

Diabetes - 1 Oct 2005

Concannon Patrick, Erlich Henry A, Julier Cecile, Morahan Grant, Nerup Jørn, Pociot Flemming, Todd John A, Rich Stephen S

Abstract excerpt

Type 1 diabetes is a common, multifactorial disease with strong familial clustering (genetic risk ratio [lambda(S)] approximately 15). Approximately 40% of the familial aggregation of type 1 diabetes can be attributed to allelic variation of HLA loci in the major histocompatibility complex on chromosome 6p21 (locus-specific lambda(S) approximately 3). Three other disease susceptibility loci have been clearly...

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Source

Identifiers

PMID: 16186404
DOI: 10.2337/diabetes.54.10.2995

Genes

CTLA4
INS
PTPN22

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Type 1 diabetes: evidence for susceptibility loci from four genome-wide linkage scans in 1,435 multiplex families.PMID 16186404Read ↗

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