Article
Replication of genome-wide association studies (GWAS) loci for fasting plasma glucose in African-Americans.
Diabetologia - 1 Apr 2011
Ramos E, Chen G, Shriner D, Doumatey A, Gerry N P, Herbert A, Huang H, Zhou J, Christman M F, Adeyemo A, Rotimi C
Abstract excerpt
AIMS/HYPOTHESIS: Chronically elevated blood glucose (hyperglycaemia) is the primary indicator of type 2 diabetes, which has a prevalence that varies considerably by ethnicity in the USA, with African-Americans disproportionately affected. Genome-wide association studies (GWASs) have significantly enhanced our understanding of the genetic basis of diabetes and related traits, including fasting plasma glucose...
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