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Article

Two genetic determinants acquired late in Mus evolution regulate the inclusion of exon 5, which alters mouse APOBEC3 translation efficiency.

PLoS pathogens - 1 Jan 2012

Li Jun, Hakata Yoshiyuki, Takeda Eri, Liu Qingping, Iwatani Yasumasa, Kozak Christine A, Miyazawa Masaaki

Abstract excerpt

Mouse apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like editing complex 3 (mA3), an intracellular antiviral factor, has 2 allelic variations that are linked with different susceptibilities to beta- and gammaretrovirus infections among various mouse strains. In virus-resistant C57BL/6 (B6) mice, mA3 transcripts are more abundant than those in susceptible BALB/c mice both in the spleen and bone...

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Identifiers

PMID: 22275865
DOI: 10.1371/journal.ppat.1002478
PMCID: PMC3262013

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Two genetic determinants acquired late in Mus evolution regulate the inclusion of exon 5, which alters mouse APOBEC3 translation efficiency.PMID 22275865Read ↗

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