Article
Mouse endogenous retroviruses can trigger premature transcriptional termination at a distance.
Genome research - 1 May 2012
Li Jingfeng, Akagi Keiko, Hu Yongjun, Trivett Anna L, Hlynialuk Christopher J W, Swing Deborah A, Volfovsky Natalia, Morgan Tamara C, Golubeva Yelena, Stephens Robert M, Smith David E, Symer David E
Abstract excerpt
Endogenous retrotransposons have caused extensive genomic variation within mammalian species, but the functional implications of such mobilization are mostly unknown. We mapped thousands of endogenous retrovirus (ERV) germline integrants in highly divergent, previously unsequenced mouse lineages, facilitating a comparison of gene expression in the presence or absence of local insertions. Polymorphic ERVs occur...
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