Article
Head injury, α-synuclein Rep1, and Parkinson's disease.
Annals of neurology - 1 Jan 2012
Goldman Samuel M, Kamel Freya, Ross G Webster, Jewell Sarah A, Bhudhikanok Grace S, Umbach David, Marras Connie, Hauser Robert A, Jankovic Joseph, Factor Stewart A, Bressman Susan, Lyons Kelly E, Meng Cheryl, Korell Monica, Roucoux Diana F, Hoppin Jane A, Sandler Dale P, Langston J William, Tanner Caroline M
Abstract excerpt
OBJECTIVE: To test the hypothesis that variability in SNCA Rep1, a polymorphic dinucleotide microsatellite in the promoter region of the gene encoding α-synuclein, modifies the association between head injury and Parkinson's disease (PD) risk. METHODS: Participants in the Farming and Movement Evaluation (FAME) and the Study of Environmental Association and Risk of Parkinsonism using Case-Control Historical...
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