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Article

Fibrinogen and factor XIII A-subunit genotypes interactively influence C-reactive protein levels during inflammation.

Annals of the rheumatic diseases - 1 Jul 2012

Hoppe Berthold, Häupl Thomas, Skapenko Alla, Ziemer Sabine, Tauber Rudolf, Salama Abdulgabar, Schulze-Koops Hendrik, Burmester Gerd-Rüdiger, Dörner Thomas

Abstract excerpt

OBJECTIVE: Fibrinogen is a target of autoimmune reactions in rheumatoid arthritis (RA). Fibrin(ogen) derivatives are involved in inflammatory processes and the generation of a stable fibrin network is necessary for sufficient inflammation control. As the density and stability of fibrin networks depend on complex interactions between factor XIIIA (F13A) and fibrinogen genotypes, the authors studied whether these...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22267327
DOI: 10.1136/annrheumdis-2011-200738

Genes

CRP
FGB
FGA

Variants

rs6050

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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