Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Bivariate genome-wide association study of circulating fibrinogen and C-reactive protein levels.

Journal of thrombosis and haemostasis : JTH - 1 Dec 2024

Hahn Julie, Temprano-Sagrera Gerard, Hasbani Natalie R, Ligthart Symen, Dehghan Abbas, Wolberg Alisa S, Smith Nicholas L, Sabater-Lleal Maria, Morrison Alanna C, de Vries Paul S

Abstract excerpt

BACKGROUND: Fibrinogen and C-reactive protein (CRP) play an important role in inflammatory pathways and share multiple genetic loci reported in previously published genome-wide association studies (GWAS), highlighting their common genetic background. Leveraging the shared biology may identify further loci pleiotropically associated with both fibrinogen and CRP. OBJECTIVES: To identify novel genetic variants that...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Biomarkers

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to C-Reactive Protein

Share to Fibrinogen

Share to Genetic Pleiotropy

Share to Genetic Predisposition to Disease

Share to Genome-Wide Association Study

Share to Polymorphism, Single Nucleotide

Source

Open in PubMed Open full text

Identifiers

PMID: 39299614
DOI: 10.1016/j.jtha.2024.08.021
PMCID: PMC12009655

Genes

CRP
ARL14EP
MICU1
NR1I2
PGM5
SOCS2
ZZZ3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Bivariate genome-wide association study of circulating fibrinogen and C-reactive protein levels.PMID 39299614Read ↗

Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation.Semantic proximity Read ↗

Novel loci, including those related to Crohn disease, psoriasis, and inflammation, identified in a genome-wide association study of fibrinogen in 17 686 women: the Women's Genome Health Study.Semantic proximity Read ↗

Pleiotropic genetic architecture and novel loci for C-reactive protein levels.Semantic proximity Read ↗

Whole-genome analysis of plasma fibrinogen reveals population-differentiated genetic regulators with putative liver roles.Semantic proximity Read ↗

Multiancestral analysis of inflammation-related genetic variants and C-reactive protein in the population architecture using genomics and epidemiology study.Semantic proximity Read ↗

Pleiotropy among common genetic loci identified for cardiometabolic disorders and C-reactive protein.Semantic proximity Read ↗

Whole genome analysis of plasma fibrinogen reveals population-differentiated genetic regulators with putative liver rolesSemantic proximity Read ↗

Association of novel genetic Loci with circulating fibrinogen levels: a genome-wide association study in 6 population-based cohorts.Semantic proximity Read ↗

Identification of gene-gene and gene-environment interactions within the fibrinogen gene cluster for fibrinogen levels in three ethnically diverse populations.Semantic proximity Read ↗

Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels.Semantic proximity Read ↗

Genome-wide linkage analysis of cardiovascular disease biomarkers in a large, multigenerational family.Semantic proximity Read ↗

A meta-analysis of 120 246 individuals identifies 18 new loci for fibrinogen concentration.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.