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Article

4G/5G polymorphism modulates PAI-1 circulating levels in obese women.

Molecular and cellular biochemistry - 1 May 2012

Fernandes Karla S, Sandrim Valéria C

Abstract excerpt

The increase in plasminogen activator inhibitor type 1 (PAI-1) has been described as a risk factor to thrombosis-related diseases. In addition, it has been demonstrated that the variant 4G of polymorphism 4G/5G located in promoter region of PAI-1 gene is associated with higher PAI-1 levels. We investigate the role of this polymorphism on circulating PAI-1 concentration in a population of 57 obese women (23%,...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22258825
DOI: 10.1007/s11010-012-1230-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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4G/5G polymorphism modulates PAI-1 circulating levels in obese women.PMID 22258825Read ↗

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