Article
Association of NOS2 and potential effect of VEGF, IL6, CCL2 and IL1RN polymorphisms and haplotypes on susceptibility to GCA--a simultaneous study of 130 potentially functional SNPs in 14 candidate genes.
Rheumatology (Oxford, England) - 1 May 2012
Enjuanes Anna, Benavente Yolanda, Hernández-Rodríguez José, Queralt Carme, Yagüe Jordi, Jares Pedro, de Sanjosé Silvia, Campo Elias, Cid Maria C
Abstract excerpt
OBJECTIVE: Frequent genetic variants may be associated with GCA. Existing studies have analysed a limited number of candidate genes and genetic variants. To expand this information, we performed a case-control study genotyping 130 single nucleotide polymorphisms (SNPs) in 82 biopsy-proven GCA patients and 166 healthy controls from the Spanish population. METHODS: SNPs in coding and regulatory gene regions of 14...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.