Article
Frequencies of single nucleotide polymorphisms in genes regulating inflammatory responses in a community-based population.
BMC genetics - 14 Mar 2007
Huang Han-Yao, Thuita Lucy, Strickland Paul, Hoffman Sandra C, Comstock George W, Helzlsouer Kathy J
Abstract excerpt
BACKGROUND: Allele frequencies reported from public databases or articles are mostly based on small sample sizes. Differences in genotype frequencies by age, race and sex have implications for studies designed to examine genetic susceptibility to disease. In a community-based cohort of 9,960 individuals, we compared the allele frequencies of 49 single nucleotide polymorphisms (SNPs) of genes involved in...
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