Article
Application of multi-SNP approaches Bayesian LASSO and AUC-RF to detect main effects of inflammatory-gene variants associated with bladder cancer risk.
PloS one - 1 Jan 2013
de Maturana Evangelina López, Ye Yuanqing, Calle M Luz, Rothman Nathaniel, Urrea Víctor, Kogevinas Manolis, Petrus Sandra, Chanock Stephen J, Tardón Adonina, García-Closas Montserrat, González-Neira Anna, Vellalta Gemma, Carrato Alfredo, Navarro Arcadi, Lorente-Galdós Belén, Silverman Debra T, Real Francisco X, Wu Xifeng, Malats Núria
Abstract excerpt
The relationship between inflammation and cancer is well established in several tumor types, including bladder cancer. We performed an association study between 886 inflammatory-gene variants and bladder cancer risk in 1,047 cases and 988 controls from the Spanish Bladder Cancer (SBC)/EPICURO Study. A preliminary exploration with the widely used univariate logistic regression approach did not identify any...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.