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Article

Influence of the inducible nitric oxide synthase gene (NOS2A) on inflammatory bowel disease susceptibility.

Immunogenetics - 1 Nov 2007

Martín M Carmen, Martinez Alfonso, Mendoza J Luis, Taxonera Carlos, Díaz-Rubio Manuel, Fernández-Arquero Miguel, de la Concha Emilio G, Urcelay Elena

Abstract excerpt

The great amount of nitric oxide (NO) produced by the inducible isoform of NO synthase (iNOS) exerts deleterious effects, and iNOS expression is raised in the colonic mucosa of inflammatory bowel disease (IBD) patients. This is the first association analysis of polymorphisms within the NOS2A extended gene with IBD susceptibility. We analyzed 336 patients of Crohn's disease (CD), 355 of ulcerative colitis (UC),...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 17955236
DOI: 10.1007/s00251-007-0255-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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