Replication of the SH2B1 rs7498665 association with obesity in a Belgian study population.

Abstract excerpt

OBJECTIVE: SH2B1 has been identified as an interesting candidate gene for complex obesity through genome-wide association studies. Therefore, we set out to replicate the reported association with rs7498665 in our Belgian study population and to extend our study with an additional tagSNP for the SH2B1 gene region. METHODS: We genotyped both rs7498665 and rs7201929 in a population of 1,045 obese adults and 317...