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Article

Screening for coding variants in FTO and SH2B1 genes in Chinese patients with obesity.

PloS one - 1 Jan 2013

Zheng Zhaojing, Hong Li, Huang Xiaodong, Yang Peirong, Li Juan, Ding Yu, Yao Ru-En, Geng Juan, Shen Yongnian, Shen Yiping, Fu Qihua, Yu Yongguo

Abstract excerpt

OBJECTIVE: To investigate potential functional variants in FTO and SH2B1 genes among Chinese children with obesity. METHODS: Sanger sequencing of PCR products of all FTO and SH2B1 exons and their flanking regions were performed in 338 Chinese Han children with obesity and 221 age- and sex-matched lean controls. RESULTS: A total of seven and five rare non-synonymous variants were identified in FTO and SH2B1,...

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Share to Adaptor Proteins, Signal Transducing
Share to Alpha-Ketoglutarate-Dependent Dioxygenase FTO

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23825611
DOI: 10.1371/journal.pone.0067039
PMCID: PMC3692548

Genes

FTO

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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