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Article

Investigating genetic variants in early-onset obesity through exome sequencing: A retrospective cohort study.

Obesity research & clinical practice - 1 Jan 2024

Liu Deyun, Liu Yuxiang, Lu Chen Yu, Wang Qian, Bao Yingying, Yu Yue, Wang Qiang, Peng Wu

Abstract excerpt

OBJECTIVE: This study aimed to examine clinical data and analyze exome sequencing (ES) findings in children diagnosed with early-onset obesity. METHODS: We screened children presenting with severe (body mass index-standard deviation score >3) and early-onset (<7 years) obesity using ES. Participants were categorized into either the "no variant identified" group or the "variant identified" group, facilitating the...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 39667993
DOI: 10.1016/j.orcp.2024.12.001

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SH2B1

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